Inheritance patterns and basics of Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy is a genetic disorder because often a single gene change creates the cardiac muscle hypertrophy.  While initially there would be negligible or little obstruction to blood flow from the left ventricular outflow, a small percentage of patients would progress to increasing obstruction.  A further small subset of these patients ultimately develop symptoms of breathlessness, palpitations, dizziness, chest pain or even death.

The link below provides clear information about genetics of HCM and is a worthwhile read.

Posted on February 3, 2013 .